Wednesday, September 1, 2010

Are drugs working for your diagnosed mental illnesses?

Post your clinically diagnosed mental disorders, and whether or not you think medication like is a crutch you will need for the rest of your life, or a temporary solution to a temporary problem.
Please be honest with us and yourself.
My basic understanding of how the human brain works:
-Each mode of human behavior is based upon patterns of neurons we grew to fit a particular situation, or instances similar to it. The more we use these neural pathways, the easier it gets to "compute" that thought process as more neurons are added to the network. These networks expand and connect with other networks; this is the basis of all learning, scholarly or otherwise.
-The neural networks we build in the various learning centers inside the brain communicate to each other with chemical signals. If certain areas of the brain are deprived of these chemical signals then a person's entire biochemistry can be changed, resulting in lack of energy, appetite, and so on.
-Drugs can replace these chemical signals and are a temporary solution which may help in the short-term, but in my opinion can actually make the problem worse given continual use without decreasing dosages. Eventually, like any drug addict, the person is back to where they started, except they have greater difficulty creating new neural networks and changing existing ones. Without the drug they cannot function normally, whereas before they could sometimes feel stable with occasional bouts of panic, anxiety, depression or whatever. normal feelings that every human experiences.
I have never been diagnosed with a mental disorder, but I am fairly positive that these are normal feelings that every human experiences to varying degrees.




I should add that I have dated girls with some serious baggage, like hardcore baggage that they felt necessitated clinical aid. One was sexually abused by her step dad during her prepubescent years, and another couple of times by friends' parents. Another cut herself and frequently ran away from her single mother's home, but I never did find out what happened in her past.

You can create new paths in the brain and stop using old ones on your free will.

You can create new paths in the brain and stop using old ones on your free will.

Try telling that to a girl who has been on Paxil for 10 years :(

I have BDP
It makes me act like a pseudo-sociopath/narcissist and moody douchebag in general. Psychotherapy is the only form of treatment that is deemed effective.

Depression with likely psychosis. If my EEG comes back clean theyre putting me on anti psychotics. Which is likely.

Mainly depression and anxiety, I've had some psychotic episodes too and can get paranoid quite easily too.
My Dad had serious depression when I was a kid so I might have 'learnt' it from him or maybe there are some genetics there, he has been on Prozac (varying doses) for about 20 years.
I take no meds anymore, all they did was make me zombified and hungry. I did a course in Cognitive Behavioral Therapy last year a Anxiety Management in a group.
Feels god not to rely on meds.

Protip antidepressants are only clinically appropriate in 1/3 of patients.
All antidepressants have very similar efficacy. So the americans promoting LOLCIPRALEX etc are just extorting the general public for a premium.
Biggest healthcare scam ever.
Most people will alternate between "normal" and depressive states, its human nature.
Now everyone whines like a bitch about it claiming they have "depression". The doctor is practically obliged to prescribe you completely inappropriate medication, due to all the armchair doctors around saying LOLdepression I need citalopram, venlafaxine etc etc.
Also the seretonergic hypothesis of depression is incredibly flawed. Infact if you have read and understand the studies it is quite shocking really.
tl:dr antidepressants are a waste of time. Ask anyone with any knowledge of neuropharmacology.


Try telling that to a girl who has been on Paxil for 10 years :(


Try telling that to a girl who has been on Paxil for 10 years :(


Try telling that to a girl who has been on Paxil for 10 years :(


Try telling that to a girl who has been on Paxil for 10 years :(

Your just an anti depressant addict, try taking a month off your meds... OH WAIT! YOUR AN ADDICT! LOLOLOLOLOLOLOL

Protip antidepressants are only clinically appropriate in 1/3 of patients.
All antidepressants have very similar efficacy. So the americans promoting LOLCIPRALEX etc are just extorting the general public for a premium.
Biggest healthcare scam ever.
Most people will alternate between "normal" and depressive states, its human nature.
Now everyone whines like a bitch about it claiming they have "depression". The doctor is practically obliged to prescribe you completely inappropriate medication, due to all the armchair doctors around saying LOLdepression I need citalopram, venlafaxine etc etc.
Also the seretonergic hypothesis of depression is incredibly flawed. Infact if you have read and understand the studies it is quite shocking really.
tl:dr antidepressants are a waste of time. Ask anyone with any knowledge of neuropharmacology.

This is me
Mainly depression and anxiety, I've had some psychotic episodes too and can get paranoid quite easily too.
My Dad had serious depression when I was a kid so I might have 'learnt' it from him or maybe there are some genetics there, he has been on Prozac (varying doses) for about 20 years.
I take no meds anymore, all they did was make me zombified and hungry. I did a course in Cognitive Behavioral Therapy last year a Anxiety Management in a group.
Feels god not to rely on meds.

I agree totally, there are a lot of people who take the meds without any sort of therapy. There is no point, you might as well be an alcoholic.
My Dad encouraged me to get on meds because it worked for me but they made me worse in my opinion.

instead of being addicted to anti depressants, just smoke some weed, f**k.
Worked for me, and i can be sober anytime i want and not feel sick and faint, rofl
<--- been sober for 8 days... just another tollerance break, gona be 3 weeks this time i think

instead of being addicted to anti depressants, just smoke some weed, f**k.
Worked for me, and i can be sober anytime i want and not feel sick and faint, rofl
<--- been sober for 8 days... just another tollerance break, gona be 3 weeks this time i think

Yeah i do tolerance breaks with f**s and weed

Antidepressants: russian roulette.

Whats even more stupid is back in the day people were put on MAOIs for depression.
While taking them a slice of cheese can kill you.
Not cool.

instead of being addicted to anti depressants, just smoke some weed, f**k.
Worked for me, and i can be sober anytime i want and not feel sick and faint, rofl
<--- been sober for 8 days... just another tollerance break, gona be 3 weeks this time i think

Weed messes with my head nowadays, I get too paranoiadised

i've had chronic depression since i was 12, as well as panic disorder. i take medication for something unrelated that just happens to help with those two things. i don't feel that meds are necessary to help depression though; simple things like a healthy diet and regular exercise can help tremendously.

Weed is not a suitable anti depressant.
I hate when stoners think weed is some magic cure all.
Its funny how no synthetic cannabanoids are used in therapy for depression.




Your just an anti depressant addict, try taking a month off your meds... OH WAIT! YOUR AN ADDICT! LOLOLOLOLOLOLOL

I wasn't referring to myself, but a girl I know. You dumbf**k.

Weed is not a suitable anti depressant.
I hate when stoners think weed is some magic cure all.
Its funny how no synthetic cannabanoids are used in therapy for depression.

Weed doesn't MAKE you happy, which anti-depressant do.


Weed doesn't MAKE you happy, which anti-depressant do.

I'm pretty sure weed makes me happy bra


Weed doesn't MAKE you happy, which anti-depressant do.

>implying anti depressants make you happy and dont just increase the amount of certian chemicals in the brain.
happiness is just perception

Weed is not a suitable anti depressant.
I hate when stoners think weed is some magic cure all.
Its funny how no synthetic cannabanoids are used in therapy for depression.

Because to do so would be career suicide. Doctors have recently revitalized their treatment of mental patients with psychoactive drugs like LSD, because such clinical trials have shown promise on the past. We already know weed is good for glaucoma, cancer patients, people in severe pain say it's one of the only relief they can find. It's only a matter of time before weed starts being tested on people diagnosed with mental disorders to see if any medicinal value can be found. Several studies have shown that it can jump-start exacerbate pre-existing disorders in some patients, which is why pharmacologists are reluctant to test its possible beneficial effects on their patients.

OP, your third point doesn't happen. Your brain doesn't get used to psychiatric drugs the same way it does to a drug like Morphine or Amphetamine. When you first start it, you will likely need to increase the dosage a little bit, but once you get to the maxomum recommended dosage, you don't go any higher. You stay at that dose for the remainder of the time you take the drug. It doesn't have to be raised after that.
Saying that they can't function without the drug is only partially true. For example with SSRI's, there IS withdrawal symptoms, but as long as you taper off the drug in a professional manner, the withdrawal can be minimized.
You say that Anxiety, Depression etc are all normal human feelings. Yes, you are correct. But there is a huge difference between feeling depressed, and having Depression. One is clinical, one isn't.
A better example for this would be Schizophrenia. The delusions and hallucinations Schizophrenics endure are caused by an excess amount of Dopamine in the brain. Antipsychotics are prescribed to lower the amount of Dopamine, which eliminates the hallucinations and delusions. The Schizophrenic can't simply tell his brain to stop making so much Dopamine, it's a problem that goes beyond psychological and into neurological. The same goes for someone with CLINICAL Depression; you can't just tell your brain to start making more Serotonin. This goes for a great many psychiatric disorders.
And finally, too many people here about drugs and instantly think "A PILL ISN'T GOING TO SOLVE ALL YOUR PROBLEMS". And they are right, to a degree. The point of psychiatric medication is that they are to be taken along with therapy. Too many people get prescribed an SSRI like Sertraline and think "all I have to do is take this pill and I'll be totally happy!" but it doesn't work that way. Therapy can work without medication, and medication can work without therapy, but it's always best to use both together whenever possible.

Coninuing from
OP, your third point doesn't happen. Your brain doesn't get used to psychiatric drugs the same way it does to a drug like Morphine or Amphetamine. When you first start it, you will likely need to increase the dosage a little bit, but once you get to the maxomum recommended dosage, you don't go any higher. You stay at that dose for the remainder of the time you take the drug. It doesn't have to be raised after that.
Saying that they can't function without the drug is only partially true. For example with SSRI's, there IS withdrawal symptoms, but as long as you taper off the drug in a professional manner, the withdrawal can be minimized.
You say that Anxiety, Depression etc are all normal human feelings. Yes, you are correct. But there is a huge difference between feeling depressed, and having Depression. One is clinical, one isn't.
A better example for this would be Schizophrenia. The delusions and hallucinations Schizophrenics endure are caused by an excess amount of Dopamine in the brain. Antipsychotics are prescribed to lower the amount of Dopamine, which eliminates the hallucinations and delusions. The Schizophrenic can't simply tell his brain to stop making so much Dopamine, it's a problem that goes beyond psychological and into neurological. The same goes for someone with CLINICAL Depression; you can't just tell your brain to start making more Serotonin. This goes for a great many psychiatric disorders.
And finally, too many people here about drugs and instantly think "A PILL ISN'T GOING TO SOLVE ALL YOUR PROBLEMS". And they are right, to a degree. The point of psychiatric medication is that they are to be taken along with therapy. Too many people get prescribed an SSRI like Sertraline and think "all I have to do is take this pill and I'll be totally happy!" but it doesn't work that way. Therapy can work without medication, and medication can work without therapy, but it's always best to use both together whenever possible.




Your just an anti depressant addict, try taking a month off your meds... OH WAIT! YOUR AN ADDICT! LOLOLOLOLOLOLOL

Yeah, and Diabetics are obviously Insulin addicts too, right?
Protip antidepressants are only clinically appropriate in 1/3 of patients.
All antidepressants have very similar efficacy. So the americans promoting LOLCIPRALEX etc are just extorting the general public for a premium.
Biggest healthcare scam ever.
Most people will alternate between "normal" and depressive states, its human nature.
Now everyone whines like a bitch about it claiming they have "depression". The doctor is practically obliged to prescribe you completely inappropriate medication, due to all the armchair doctors around saying LOLdepression I need citalopram, venlafaxine etc etc.
Also the seretonergic hypothesis of depression is incredibly flawed. Infact if you have read and understand the studies it is quite shocking really.
tl:dr antidepressants are a waste of time. Ask anyone with any knowledge of neuropharmacology.

>Also the seretonergic hypothesis of depression is incredibly flawed. Infact if you have read and understand the studies it is quite shocking really.
You are the first person I have ever met who claims the Seretonergic theory for Depression is flawed. Care to show me these "studies" you speak of?

Armchair doctors are hilarious. Alright you young male adult with little to no formal training in the matter, I will take your opinions presented aggressively without facts as religion and concede all of your points. God damn.

Depersonalization disorder. Psychosis when I get extremely stressed. Pathological lying. I hve no friends.

OP, your third point doesn't happen. Your brain doesn't get used to psychiatric drugs the same way it does to a drug like Morphine or Amphetamine. When you first start it, you will likely need to increase the dosage a little bit, but once you get to the maxomum recommended dosage, you don't go any higher. You stay at that dose for the remainder of the time you take the drug. It doesn't have to be raised after that.
Saying that they can't function without the drug is only partially true. For example with SSRI's, there IS withdrawal symptoms, but as long as you taper off the drug in a professional manner, the withdrawal can be minimized.
You say that Anxiety, Depression etc are all normal human feelings. Yes, you are correct. But there is a huge difference between feeling depressed, and having Depression. One is clinical, one isn't.
A better example for this would be Schizophrenia. The delusions and hallucinations Schizophrenics endure are caused by an excess amount of Dopamine in the brain. Antipsychotics are prescribed to lower the amount of Dopamine, which eliminates the hallucinations and delusions. The Schizophrenic can't simply tell his brain to stop making so much Dopamine, it's a problem that goes beyond psychological and into neurological. The same goes for someone with CLINICAL Depression; you can't just tell your brain to start making more Serotonin. This goes for a great many psychiatric disorders.
And finally, too many people here about drugs and instantly think "A PILL ISN'T GOING TO SOLVE ALL YOUR PROBLEMS". And they are right, to a degree. The point of psychiatric medication is that they are to be taken along with therapy. Too many people get prescribed an SSRI like Sertraline and think "all I have to do is take this pill and I'll be totally happy!" but it doesn't work that way. Therapy can work without medication, and medication can work without therapy, but it's always best to use both together whenever possible.

Good post, thanks for contributing.
It has been mentioned in past threads that most 3rd world populations face much harsher conditions than those of us who can afford a bottle of pills every month, yet they are either entirely free of mental disorders classified by Western medicine or are undiagnosed, un-medicated, and still surviving and raising families to the best of their ability.

Coninuing from

Yeah, and Diabetics are obviously Insulin addicts too, right?

>Also the seretonergic hypothesis of depression is incredibly flawed. Infact if you have read and understand the studies it is quite shocking really.
You are the first person I have ever met who claims the Seretonergic theory for Depression is flawed. Care to show me these "studies" you speak of?

Probably because I'm one of the few on anonymous actually studying neuropharmacology.
If you read what I said properly I stated that " if you have read and understand the studies it is quite shocking really." As in the evidence FOR is flawed.
As in the only studies to PROVE this theory were
The reserpine study in 1954
And Schildkraut 1965
If you have any knowledge of clinical trials you would understand.
Suck my dick.

99% in this thread probably failed basic science


Probably because I'm one of the few on anonymous actually studying neuropharmacology.
If you read what I said properly I stated that " if you have read and understand the studies it is quite shocking really." As in the evidence FOR is flawed.
As in the only studies to PROVE this theory were
The reserpine study in 1954
And Schildkraut 1965
If you have any knowledge of clinical trials you would understand.
Suck my dick.

>Probably because I'm one of the few on anonymous actually studying neuropharmacology.
Oh u.
I didn't mean on web, you moron. I mean throughout the entire world. The thousands of students who go through school to obtain pharmaceutical and psychiatric degrees all agree with it, and then just because one student feels there's a lack of evidence it's instantly wrong? (inb4 "I'm not the only one!" I'm sure you aren't, but you're a defiante minority)
If you've got a better theory, I'd love to hear it.

I read somewhere (sorry, can't recall, probably Wikipedia) that our brain increases our DMT-level while we are dreaming, which sometimes causes weird dreams and so on. Anyone who can confirm or is this bogus?

depression couple times, many years total
social anxiety 2 years
hypervigilante random episodes for a while
thats pretty much it, depression like 100% sure,social anxiety aswell but that was just for me maybe its not truely clinically diagnosed
MEDS are for f**king fa**ots, im doing so well atm i think, if i continue to make changes and not yet f**ked up getting a degree im sure all this sh*t wont be a problem in the long run.
il add that for the medication im truly convinced taking meds hold u down, its possible to activily do something to get better, social stuff was hard and very very slow, challenging myself but it has worked, sometimes i dont think when im outside!! im still getting high heartrate and all that shti tho -.- but it gets suppresed well so its not a big deal.
depression idk but i think u do sink into it because of some stuff that happens, u just take it on an emotional level and sink really deep, really irrational. if u manage to plow tru dat and improve atleast somewhat eventually ur head comes out of the water again and u can take a nice breath :)

I read somewhere (sorry, can't recall, probably Wikipedia) that our brain increases our DMT-level while we are dreaming, which sometimes causes weird dreams and so on. Anyone who can confirm or is this bogus?

without DMT there would be no dreaming. small amounts of the chemical are released every time you go through a normal sleep cycle. a massive amount (relatively) is also released when you die.

Well other accepted theories include:
The hyperactive HPA axis theory
Hippocampal degeneration
Circardian disrhythmia
There have even been studies suggesting the role of oestrogens along with genetic influences.

Well other accepted theories include:
The hyperactive HPA axis theory
Hippocampal degeneration
Circardian disrhythmia
There have even been studies suggesting the role of oestrogens along with genetic influences.

Thanks, I'm going to look into these.


Thanks, I'm going to look into these.

Its ironic that you're calling me the moron when you are completely unaware of the numerous other theories on depression.
Go back to college.
Or maybe even high school.

Depression
OCD
Anxiety
Insomnia
Sensory Integration Disorder
Only drug I take is Xanax, and man does it help.


Its ironic that you're calling me the moron when you are completely unaware of the numerous other theories on depression.
Go back to college.
Or maybe even high school.

Try to keep it civil :)
I've struggled with depression and social anxiety in my own ways; never once have I used pharmacy drugs but I have self-medicated with weed, shrooms, and salvia. I rarely use any of those substances now, and am a happy and stable person because of them (partially at least.) Salvia in particular gave me some great insights about life, and pretty much eliminated my depression. Valuable drugs are being made illegal before their true potential is discovered; it's too bad the medical industry makes a sh*tload of money from treating illnesses rather than curing/preventing them. They might be more open-minded if $$$ wasn't such a huge motivator.


Try to keep it civil :)
I've struggled with depression and social anxiety in my own ways; never once have I used pharmacy drugs but I have self-medicated with weed, shrooms, and salvia. I rarely use any of those substances now, and am a happy and stable person because of them (partially at least.) Salvia in particular gave me some great insights about life, and pretty much eliminated my depression. Valuable drugs are being made illegal before their true potential is discovered; it's too bad the medical industry makes a sh*tload of money from treating illnesses rather than curing/preventing them. They might be more open-minded if $$$ wasn't such a huge motivator.

Haha its cool.
The drugs companies are ultimately extorting people for their gain though, which is kind of sad.
Generic sertraline 100mg costs around 2 gbp for 28 tablets.
While the branded versions cost 30 gbp
Its a complete scam, they are identical drugs!
One area of research I do like is into new antidepressants.
There's been a few studies that proved ketamine has quite good antidepressant properties.
I just couldn't imagine taking that every day though, it would be insane.


Haha its cool.
The drugs companies are ultimately extorting people for their gain though, which is kind of sad.
Generic sertraline 100mg costs around 2 gbp for 28 tablets.
While the branded versions cost 30 gbp
Its a complete scam, they are identical drugs!
One area of research I do like is into new antidepressants.
There's been a few studies that proved ketamine has quite good antidepressant properties.
I just couldn't imagine taking that every day though, it would be insane.

It would probably best be administered in small doses and in combination with therapy. I've never had K but I hear on high doses it's like traveling the astral plane O.o


Haha its cool.
The drugs companies are ultimately extorting people for their gain though, which is kind of sad.
Generic sertraline 100mg costs around 2 gbp for 28 tablets.
While the branded versions cost 30 gbp
Its a complete scam, they are identical drugs!
One area of research I do like is into new antidepressants.
There's been a few studies that proved ketamine has quite good antidepressant properties.
I just couldn't imagine taking that every day though, it would be insane.

>The drugs companies are ultimately extorting people for their gain though, which is kind of sad.
Pharmaceuticals is a business just like anything else. There's no reason for it to run any different from a paper company or any other company. They all need to get paid.
However, I do agree that the price difference between generic and brand-name medication is pretty silly.
As for Depression treatment alternatives, I always thought a low dose of Amphetamine is very promising, too bad the chances of that becoming a common treatment line is unlikely.

OP I took about 7 cans of beans to treat my hunger this morning. It's the only thing I've found that works! Tried lettuce, radishes, pita bread, none of it is effective. Just beans. I have had to live with severe bouts of flatulence for the greater part of my adult life. Being diagnosed as hungry is no joke, especially when re-fried beans are the only cure.

depression, anxiety, avoidance
i dont think im "sick", they are just things about me that i would like to change that also happen to be included in the DSM IV
seeing a shrink just to have someone to talk to

OCD. Except I don't have it anymore because I made it my bitch.

OCD. Except I don't have it anymore because I made it my bitch.

Good for you <3

Whats even more stupid is back in the day people were put on MAOIs for depression.
While taking them a slice of cheese can kill you.
Not cool.

Monamide oxidase inhibitors are probably the only class of antidepressants that actually work. Plus they are really f**king health, monamide oxidase creates oxygen free radicals which enjoy to f**k up your brain.

Diagnosed with ADD, but I don't take medication for it since they don't work on me. =/


without DMT there would be no dreaming. small amounts of the chemical are released every time you go through a normal sleep cycle. a massive amount (relatively) is also released when you die.

HYPOTHESISES EVERYWHERE
but in all seriousness, near death experienced have been shown to be a result of an insane epinephrine and norepinephrine rush, or blood loss, the latter more likely.


HYPOTHESISES EVERYWHERE
but in all seriousness, near death experienced have been shown to be a result of an insane epinephrine and norepinephrine rush, or blood loss, the latter more likely.

Yep, hypovolemic shock can often cause hallucinations. Ie. "Seeing a tunnel and a white light"
Religious maniacs believe it is heaven.
When its just severe hypotension.

I'm actually surprised there has been some intelligent conversation about pharmacology here.
Bravo anonymous

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